General Information |
| Clinical trials phase |
Other |
| Start date (estimated) |
2022-01-01 |
| End date (estimated) |
2024-10-31 |
| Clinical feature |
| Label |
Acute liver failure |
| Link |
http://www.orpha.net/ORDO/Orphanet_90062 |
| Description |
A rare hepatic disease characterized by acute onset of severe liver dysfunction without evidence of underlying chronic liver disease. Patients present with nonspecific symptoms like jaundice, upper right abdominal pain, nausea, vomiting, pruritus, fatigue, and fever. The condition may rapidly progress to hepatic encephalopathy, coagulopathy, and life-threatening multiorgan failure. Liver biopsy typically shows massive hepatic necrosis. |
|
Administrative Information |
| ICTRP weblink |
https://trialsearch.who.int/Trial2.aspx?TrialID=ChiCTR2100052988 |
| Other study identifiers |
| Name |
ChiCTR2100052988 |
| Description |
Chinese Clinical Trial Registry (ChiCTR) |
|
| Source weblink |
http://www.chictr.org.cn/showprojen.aspx?proj=133608 |
| Public contact |
| Email |
70950808@qq.com |
| Public email |
70950808@qq.com |
| First name |
Sun |
| Last name |
Yi |
| Phone |
+86 731 88395675 |
| City |
Changsha |
| Country |
|
| Address freetext |
8 Luyun Road, Yuelu District, Changsha, Hunan, China |
|
| Sponsors |
Xiangya Hospital Central South University
|
Cells |
| Which differentiated cell type is used |
| Label |
hepatocyte |
| Link |
http://purl.obolibrary.org/obo/CL_0000182 |
| Description |
The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.; Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive. |
|
Recruitment |
| Recruitment Status |
Not yet recruiting |
| Estimated number of participants |
10 |
