An exploratory clinical study of islet-like cell transplantation differentiated from autologous induced pluripotent stem cells for the treatmen of type 1 diabetes

General Information

Clinical trials phase Alternative regulatory mechanism
Start date (estimated) 2023-06-11
End date (estimated) 2023-12-01
Clinical feature
Label type 1 diabetes mellitus
Description A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.; Xref MGI. OMIM mapping confirmed by DO. [SN].

Administrative Information

ICTRP weblink
Other study identifiers
Name ChiCTR2300072200
Source weblink
Public contact
Public email
First name Zhongyang
Last name Shen
Phone +86 138 0301 9898
City Tianjin
Sponsors Tianjin First Center Hospital


Which differentiated cell type is used
Label progenitor cell of endocrine pancreas
Description A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1.


Recruitment Status Recruiting
Estimated number of participants 3