An exploratory clinical study of islet-like cell transplantation differentiated from autologous induced pluripotent stem cells for the treatmen of type 1 diabetes

General Information
Clinical trials phase	Alternative regulatory mechanism
Start date (estimated)	2023-06-11
End date (estimated)	2023-12-01
Clinical feature	Label type 1 diabetes mellitus Link http://purl.obolibrary.org/obo/DOID_9744 Description A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.; Xref MGI. OMIM mapping confirmed by DO. [SN].
Publications	Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient
Administrative Information
ICTRP weblink	https://trialsearch.who.int/Trial2.aspx?TrialID=ChiCTR2300072200
Other study identifiers	Name ChiCTR2300072200
Source weblink	https://www.chictr.org.cn/showproj.html?proj=192835
Sponsors	Tianjin First Center Hospital
Cells
Which differentiated cell type is used	Label progenitor cell of endocrine pancreas Link http://purl.obolibrary.org/obo/CL_0002351 Description A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1.
Recruitment
Recruitment Status	Recruiting
Estimated number of participants	3