Clinical trial of human (allogeneic) iPS cell-derived cardiomyocytes sheet for dilated cardiomyopathy

Clinical trials phase

Phase 1

Start date (estimated)

2023-11-25

Clinical feature

Label	dilated cardiomyopathy
Link	http://purl.obolibrary.org/obo/DOID_12930
Description	An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.; Xref MGI. OMIM mapping confirmed by DO. [LS].

Other study identifiers

Name	jRCT2053230136
Description	Japan Registry of Clinical Trials (jRCT)

Source weblink

Public contact

saisentan@tissue.med.osaka-u.ac.jp

Public email

saisentan@tissue.med.osaka-u.ac.jp

First name

Takuji

Last name

Kawamura

Phone

+81-6-6879-3154

City

Osaka

Country

Japan

Address freetext

2-15, Yamadaoka, Suita, Osaka 565-0871 Osaka Japan

Which differentiated cell type is used

Label	cardiac muscle cell
Link	http://purl.obolibrary.org/obo/CL_0000746
Description	Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.; This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction.

Recruitment Status

Recruiting

Estimated number of participants