General Information |
| Summary |
This is a clinical study on the use of iNK cells for the treatment of refractory relapsed acute myeloid leukemia. |
| Description |
Natural killer (NK) cells are lymphocytes of the innate immune system and could recognize and kill a wide range of cells in distress, particularly tumour cells and cells infected with viruses. Induced pluripotent setm cells(iPSCs) derived NK cells have better proliferative capacity and homogeneity than donor peripheral blood or umbilical cord blood derived NK cells. We conduct this clinical study to evaluate the efficacy and safety of INK cells in the treatment of acute myeloid leukemia and our purpose is to find new treatment option. |
| Clinical trials phase |
Early Phase 1 |
| Start date (estimated) |
2024-11-25 |
| End date (estimated) |
2026-11-24 |
| Clinical feature |
| Label |
acute myeloid leukemia |
| Link |
http://purl.obolibrary.org/obo/DOID_9119 |
| Description |
A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.; OMIM mapping confirmed by DO. [SN]. |
|
Administrative Information |
| NCT number |
NCT06702098 |
| ICTRP weblink |
https://trialsearch.who.int/Trial2.aspx?TrialID=NCT06702098 |
| Other study identifiers |
|
| Source weblink |
https://clinicaltrials.gov/study/NCT06702098 |
| Public contact |
| Email |
332520646@qq.com |
| Public email |
332520646@qq.com |
| First name |
Liu J Jianbo |
| Last name |
Liu |
| Phone |
+86-020-85959142 |
|
| Sponsors |
Guangzhou Ruixin Biotechnological Co., LTD
|
| Collaborators |
|
Cells |
| Which differentiated cell type is used |
| Label |
natural killer cell |
| Link |
http://purl.obolibrary.org/obo/CL_0000623 |
| Description |
A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. |
|
Recruitment |
| Recruitment Status |
Not yet recruiting |
| Estimated number of participants |
10 |
