General Information |
| Description |
In this trial of retinal pigment epithelium (RPE) replacement, the aim will be to evaluate the safety and feasibility/efficacy of treating subjects with exudative age-related macular degeneration (AMD) by transplanting autologous iPSC derived RPE sheets. |
| Clinical trials phase |
Other |
| Start date (estimated) |
2013-10-02 |
| End date (estimated) |
2019-02-28 |
| Clinical feature |
| Label |
age related macular degeneration |
| Link |
http://purl.obolibrary.org/obo/DOID_10871 |
| Description |
A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.; OMIM mapping confirmed by DO. [SN]. |
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| Publications |
|
Administrative Information |
| ICTRP weblink |
https://trialsearch.who.int/Trial2.aspx?TrialID=JPRN-UMIN000011929 |
| Other study identifiers |
| Name |
UMIN000011929 |
| Description |
UMIN Clinical Trials Registry (UMIN-CTR) |
|
| Source weblink |
https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013279 |
| Public contact |
| Email |
hirami@fbri.org |
| First name |
Yasuhiko |
| Last name |
Hirami |
| Phone |
078-302-4321 |
| City |
Kobe |
| Country |
|
| Address freetext |
Kobe City Medical Center General Hospital |
|
| Sponsors |
Riken
|
Cells |
| Which differentiated cell type is used |
| Label |
retinal pigment epithelial cell |
| Link |
http://purl.obolibrary.org/obo/CL_0002586 |
| Description |
An epithelial cell of the retinal pigmented epithelium. |
|
Recruitment |
| Recruitment Status |
Completed |
| Comment recruitment status |
The trial was halted after two patients because of Japan's Regenerative Medicine Law of 2014. (Estimated number of participants was 6). |
| Estimated number of participants |
2 |
