Clinical Trial of Human Neural Precursor Cell (hNPC) Transplantation for Ischemic Brain Injury(——A Clinical Trial Evaluating the Safety, Tolerability, and Efficacy of hNPC01 Injection Derived from Human Induced Pluripotent Stem Cells in Improving Hemiplegic Sequelae of Ischemic Stroke)(Phase I)

General Information
Clinical trials phase	Phase 1
Start date (estimated)	2023-10-31
End date (estimated)	2025-12-31
Clinical feature	Label Ischemic Stroke Link http://purl.obolibrary.org/obo/NCIT_C95802 Description An acute episode of focal cerebral, spinal, or retinal dysfunction caused by infarction of brain tissue.
Administrative Information
ICTRP weblink	https://trialsearch.who.int/Trial2.aspx?TrialID=ChiCTR2500106320
Other study identifiers	Name ChiCTR2500106320 Description Chinese Clinical Trial Registry
Source weblink	https://www.chictr.org.cn/showproj.html?proj=264166
Study sites	The Seven Medical Center of PLA General Hospital
Sponsors	Neurosurgery Department of Seventh Medical Center, Senior Department of Neurosurgery, the First Medical Center of PLA General Hospital
Cells
Which differentiated cell type is used	Label neural progenitor cell Link http://purl.obolibrary.org/obo/CL_0011020 Description An undifferentiated cell derived from a neural stem cell, with a limited capacity to self-renew (Dibajnia and Morshead, 2013) and the ability to generate multiple types of lineage-restricted progenitors, contributing to the formation of neurons, astrocytes, and oligodendrocytes.
Recruitment
Recruitment Status	Completed
Estimated number of participants	9
Contact institutions/departments	Neurosurgery Department of Seventh Medical Center