Induced Pluripotent Stem Cells-derived Small Extracellular Vesicles May Promote Neurological Function and Improve Cognitive Impairment in Acute Ischemic Stroke Patients

General Information
Clinical trials phase	Phase 1
Start date (estimated)	2025-03-07
End date (estimated)	2026-01-01
Clinical feature	Label Cognitive Impairment Link http://purl.obolibrary.org/obo/NCIT_C116921 Description Diminished mental function.
Administrative Information
NCT number	NCT07145294
ICTRP weblink	https://trialsearch.who.int/Trial2.aspx?TrialID=NCT07145294
Source weblink	https://clinicaltrials.gov/study/NCT07145294
Study sites	Shanghai Sixth Hospital
Sponsors	Hongmei Wang
Cells
Which differentiated cell type is used	Label Extracellular Vesicle Link http://purl.obolibrary.org/obo/NCIT_C153165 Description Bilayer membrane fragments present in the blood plasma that are released by different cell types upon activation or death. Extracellular vesicles are usually classified as either exosomes (formed by the membranes of intracellular compartments, 50-100 nm in diameter) and ectosomes (also called microparticles or microvesicles, formed from plasma membrane, 100-1000 nm in diameter).
Recruitment
Recruitment Status	Recruiting
Estimated number of participants	40