A Prospective Study on Induced Pluripotent Stem Cell-Derived Exosomes for the Treatment of Diabetic Peripheral Neuropathy

General Information

Clinical trials phase Phase 1
Start date (estimated) 2025-09-08
End date (estimated) 2026-12-31
Clinical feature
Label diabetic neuropathy
Link http://purl.obolibrary.org/obo/MONDO_0006626
Description A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Administrative Information

ICTRP weblink https://trialsearch.who.int/Trial2.aspx?TrialID=ChiCTR2500108862
Other study identifiers
Name ChiCTR2500108862
Description Chinese Clinical Trial Registry
Source weblink https://www.chictr.org.cn/showproj.html?proj=285996
Study sites
Sponsors Beijing Hospital, National Center of Gerontology

Cells

Which differentiated cell type is used
Label Exosome
Link http://purl.obolibrary.org/obo/NCIT_C104457
Description A secretory vesicle between 30 and 90 nm in diameter that can play a role in receptor recycling, plasma membrane protein shedding, and the secretion of proteins and RNA.

Recruitment

Recruitment Status Not yet recruiting
Comment recruitment status Intervention group:20;Control group:20
Estimated number of participants 40