General Information |
| Description |
The objectives of this clinical study are to evaluate the safety as well as the feasibility and visual function efficacy of transplantation of RPE cells differentiated from allogenic iPS cells induced from the peripheral blood of 6 HLA locus homozygous donor for HLA haplotype matched subjects with neovascular AMD. |
| Clinical trials phase |
Other |
| Start date (estimated) |
2017-02-06 |
| End date (estimated) |
2021-09-20 |
| Clinical feature |
| Label |
age related macular degeneration |
| Link |
http://purl.obolibrary.org/obo/DOID_10871 |
| Description |
A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.; OMIM mapping confirmed by DO. [SN]. |
|
| Publications |
|
Administrative Information |
| ICTRP weblink |
https://trialsearch.who.int/Trial2.aspx?TrialID=JPRN-UMIN000026003 |
| Other study identifiers |
| Name |
UMIN000026003 |
| Description |
UMIN Clinical Trials Registry（UMIN-CTR） |
|
| Source weblink |
https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000029894 |
| Public contact |
| Email |
e_kenkyujimu@kcho.jp |
| Public email |
e_kenkyujimu@kcho.jp |
| First name |
Naoki |
| Last name |
Shibatani |
| City |
Kobe |
| Country |
|
| Address freetext |
2-1-8, Manatojima-minamimachi, Chuo-ku, Kobe Japan 650-0047 Japan |
|
| Sponsors |
Riken
Kobe City Medical Center General Hospital
Osaka University Hospital
Center for iPS Cell Research and Application
|
Cells |
| Which differentiated cell type is used |
| Label |
retinal pigment epithelial cell |
| Link |
http://purl.obolibrary.org/obo/CL_0002586 |
| Description |
An epithelial cell of the retinal pigmented epithelium. |
|
Recruitment |
| Recruitment Status |
Completed |
| Comment recruitment status |
Follow-up complete |
| Estimated number of participants |
5 |
