General Information |
Summary |
This project intends to transplant a clinical level human embryonic stem cells derived retinal pigment epithelium into subretinal space to treat eetinitis pigmentosa(RP) diseases. |
Description |
This project intends to transplant a clinical level human embryonic stem cells derived retinal pigment epithelium into subretinal space to treat eetinitis pigmentosa(RP) diseases. Through the statistical analysis EDTRS, BCVA, OCT, ERG, Fluorescein angiography, Ophthalmic AB ultrasound changes between before and after the treatment to assess the efficacy and safety 0f RPE transplants to treat RP disease. |
Clinical trials phase |
Other |
Start date (estimated) |
2015-09-20 |
End date (estimated) |
2017-12-20 |
Clinical feature |
Label |
retinitis pigmentosa |
Link |
http://purl.obolibrary.org/obo/DOID_10584 |
Description |
A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.; Xref MGI.
OMIM mapping confirmed by DO. [LS]. |
|
Administrative Information |
Other study identifiers |
Name |
ChiCTR-OCB-15007055 |
Description |
Chinese Clinical Trial Registry (ChiCTR) |
|
Source weblink |
http://www.chictr.org.cn/hvshowproject.aspx?id=3681 |
Regulatory body approval |
Name |
National Health Commission of the PRC;National medical products administration |
Country |
|
|
Approval number |
CMR-20181112-1001 |
Study sites |
|
Public contact |
Email |
wangliu@ioz.ac.cn |
Public email |
wangliu@ioz.ac.cn |
First name |
Liu |
Last name |
Wang |
Country |
|
|
Sponsors |
Chinese Academy of Sciences |
Collaborators |
|
Cells |
Which differentiated cell type is used |
Label |
retinal pigment epithelial cell |
Link |
http://purl.obolibrary.org/obo/CL_0002586 |
Description |
An epithelial cell of the retinal pigmented epithelium. |
|
Recruitment |
Recruitment Status |
Recruiting |
Estimated number of participants |
10 |
Contact institutions/departments |
|