First-in-human clinical research of iPS derived corneal epithelial cell sheet transplantation for patients with limbal stem-cell deficiency

General Information

Description The objectives of this clinical research are to evaluate the safety as well as the feasibility and efficacy of transplantation of iPS derived corneal epithelial cell sheet (iCEPS) for LSCD patients.
Clinical trials phase Phase 1
Start date (estimated) 2019-05-01
Clinical feature
Label Limbal stem cell deficiency
Link http://purl.obolibrary.org/obo/HP_0032107
Description A condition characterized by a loss or deficiency of the stem cells in the limbus that are vital for re-population of the corneal epithelium and to the barrier function of the limbus.

Administrative Information

ICTRP weblink http://apps.who.int/trialsearch/Trial2.aspx?TrialID=JPRN-UMIN000036539
Other study identifiers
Name UMIN000036539
Description (JPRN-UMIN)
Source weblink https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000041628
Regulatory body approval
Name The First Certified Special Committee for Regenerative Medicine, Osaka University
Country
Japan
Study sites
Public contact
Email ips_cornea@ophthal.med.osaka-u.ac.jp
Public email ips_cornea@ophthal.med.osaka-u.ac.jp
First name Takeshi
Last name Soma
Phone +81 (0)6-6879-3456
City Osaka
Country
Japan
Sponsors Department of Ophthalmology, Osaka University Graduate School of Medicine

Cell Line

Recruitment

Recruitment Status Recruiting
Estimated number of participants 4
Contact institutions/departments