Safety study of induced pluripoteint stem cell-derived cardiac spheres transplantation (IPSCS study)

General Information

Clinical trials phase Other
Start date (estimated) 2020-11-09
Clinical feature
Label heart failure

Administrative Information

ICTRP weblink
Other study identifiers
Name jRCTa032200189
Description Japan Registry of Clinical Trials (jRCT)
Source weblink
Public contact
Public email
First name Yoshikazu
Last name Kishino
Phone +81-3-3353-1211
City Tokyo
Address freetext Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo
Sponsors Heartseed Inc.


Which differentiated cell type is used
Label cardiac muscle cell
Description Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.; This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction.


Recruitment Status Recruiting
Estimated number of participants 3