Human iPSC banking: barriers and opportunities
Summary
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new opportunities for regenerative medicine, disease modeling, iPSC-based drug discovery and toxicity assessment. Over the past 10 years, several initiatives have been established that aim to collect and generate a large amount of human iPSCs for scientific research purposes. In this review, we compare the construction and operation strategy of some iPSC banks as well as their ongoing development. We also introduce the technical challenges and offer future perspectives pertaining to the establishment and management of iPSC banks.
| Authors | Huang CY, Liu CL, Ting CY, Chiu YT, Cheng YC, Nicholson MW, Hsieh PCH |
|---|---|
| Journal | Journal of biomedical science |
| Publication Date | 2019 Oct 28;26(1):87 |
| PubMed | 31660969 |
| PubMed Central | PMC6819403 |
| DOI | 10.1186/s12929-019-0578-x |