Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Summary
Our hiPSC-CMs from a BrS-patient with two variants in SCN1B recapitulated some key phenotypic features of BrS and can provide a platform for studies on BrS with SCN1B variants. Copyright © 2019 El-Battrawy, Müller, Zhao, Cyganek, Zhong, Zhang, Kleinsorge, Lan, Li, Xu, Huang, Liao, Moscu-Gregor, Albers, Dinkel, Lang, Diecke, Zimmermann, Utikal, Wieland, Borggrefe, Zhou and Akin.
| Authors | El-Battrawy I, Müller J, Zhao Z, Cyganek L, Zhong R, Zhang F, Kleinsorge M, Lan H, Li X, Xu Q, Huang M, Liao Z, Moscu-Gregor A, Albers S, Dinkel H, Lang S, Diecke S, Zimmermann WH, Utikal J, Wieland T, Borggrefe M, Zhou X, Akin I |
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| Journal | Frontiers in cell and developmental biology |
| Publication Date | 2019;7:261 |
| PubMed | 31737628 |
| PubMed Central | PMC6839339 |
| DOI | 10.3389/fcell.2019.00261 |