UMGi014-B

Registration Summary:

A P E C

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General

Cell Line
hPSCreg name	UMGi014-B
Cite as:	UMGi014-B (RRID:CVCL_A4JI)
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	1st March 2022
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Provider
Generator	University Medical Center Goettingen (UMG)
External Databases
Cellosaurus	CVCL_A4JI, CVCL_A4JK, CVCL_A4JJ
Wikidata	Q105511387, Q105511390, Q105511392
General Information
Publications	El-Battrawy I et al. Modeling Short QT Syndrome Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Journal of the American Heart Association. 2018 Mar 24;7(7). El-Battrawy I et al. Electrical dysfunctions in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with an arrhythmogenic right ventricular cardiomyopathy. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2018 Jun 1;20(FI1):f46-f56. El-Battrawy I et al. Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Frontiers in cell and developmental biology. 2019;7:261. Khadjeh S et al. CRISPLD1: a novel conserved target in the transition to human heart failure. Basic research in cardiology. 2020 Mar 7;115(3):27. Huang M et al. Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy. Frontiers in cardiovascular medicine. 2021;8:777463. Sattler K et al. TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes. Scientific reports. 2021 Jul 19;11(1):14689. Zhong R et al. A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells. International journal of molecular sciences. 2022 Jul 27;23(15). Fan X et al. Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. International journal of molecular sciences. 2022 Jul 31;23(15). Li Y et al. Novel insights in the pathomechanism of Brugada syndrome and fever-related type 1 ECG changes in a preclinical study using human-induced pluripotent stem cell-derived cardiomyocytes. Clinical and translational medicine. 2023 Mar;13(3):e1130. Xu Q et al. Esophageal Cancer-Related Gene-4 Contributes to Lipopolysaccharide-Induced Ion Channel Dysfunction in hiPSC-Derived Cardiomyocytes. Journal of inflammation research. 2024;17:10183-10197.
Subclones	UMGi014-B-1 UMGi014-B-2 UMGi014-B-3 UMGi014-B-4

hIPSC Derivation

General