Modeling Short QT Syndrome Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Summary
Patient-specific hiPSC-CMs are able to recapitulate single-cell phenotype features of SQTS and provide novel opportunities to further elucidate the cellular disease mechanism and test drug effects. © 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.
Authors | El-Battrawy I, Lan H, Cyganek L, Zhao Z, Li X, Buljubasic F, Lang S, Yücel G, Sattler K, Zimmermann WH, Utikal J, Wieland T, Ravens U, Borggrefe M, Zhou XB, Akin I |
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Journal | Journal of the American Heart Association |
Publication Date | 2018 Mar 24;7(7) |
PubMed | 29574456 |
PubMed Central | PMC5907581 |
DOI | 10.1161/jaha.117.007394 |