Generation of a human induced pluripotent stem cell line from urinary cells of a healthy donor using an integration free vector
Summary
We have generated a human induced pluripotent stem cell (iPSC) line derived from urinary cells of a 30 year old healthy female donor. The cells were reprogrammed using a non-integrating viral vector and have shown full differentiation potential. Together with the iPSC-line, the donor provided blood cells for the study of immunological effects of the iPSC line and its derivatives in autologous and allogeneic settings. The line is available and registered in the human pluripotent stem cell registry as BCRTi004-A. Copyright © 2016 University of Texas at Austin Dell Medical School. Published by Elsevier B.V. All rights reserved.
| Authors | Rossbach B, Hildebrand L, El-Ahmad L, Stachelscheid H, Reinke P, Kurtz A |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2016 Mar;16(2):314-7 |
| PubMed | 27345993 |
| DOI | 10.1016/j.scr.2015.12.018 |