Derivation of the human embryonic stem cell line RCe012-A (RC-8)
Summary
The human embryonic stem cell line RCe012-A (RC-8) was derived from a frozen and thawed day 5 embryo cultivated to the blastocyst stage. The embryo was voluntarily donated as unsuitable and surplus to fertility requirements following ethics committee approved informed consent under licence from the UK Human Fertilisation and Embryology Authority. The cell line shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data is available. Copyright © 2016 University of Texas at Austin Dell Medical School. Published by Elsevier B.V. All rights reserved.
| Authors | De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, Bradburn H, Downie JM, Bateman M, Courtney A |
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| Journal | Stem cell research |
| Publication Date | 2016 Mar;16(2):489-92 |
| PubMed | 27346021 |
| DOI | 10.1016/j.scr.2016.02.033 |