Derivation of the clinical grade human embryonic stem cell line RCe019-A (RC-15)
Summary
The human embryonic stem cell line RCe019-A (RC-15) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a cleavage stage embryo voluntarily donated as unsuitable or surplus to fertility requirements following informed consent. RCe019-A (RC-15) shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a mixed 46XX/47XX, +8 female karyotype and microsatellite PCR identity, HLA and blood group typing data is available. Copyright © 2016 Roslin Cells Ltd. Published by Elsevier B.V. All rights reserved.
| Authors | De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Downie JM, Bateman M, Courtney A |
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| Journal | Stem cell research |
| Publication Date | 2016 May;16(3):751-5 |
| PubMed | 27346200 |
| DOI | 10.1016/j.scr.2016.04.003 |