Genome-wide CRISPR screens for the identification of therapeutic targets for cancer treatment

Summary

The application of CRISPR-based therapeutic target screening is broadly used in cancer drug development. Its application in cancer immunotherapy and precision oncology is blooming. Nevertheless, more effective methods of Cas protein delivery and the development of more accurate and efficient genome-editing tools are needed.

Authors Xue VW, Wong SCC, Cho WCS
Journal Expert opinion on therapeutic targets
Publication Date 2020 Sep 17;:1-12
PubMed 32893711
DOI 10.1080/14728222.2020.1820986

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