Genome-wide CRISPR screens for the identification of therapeutic targets for cancer treatment
The application of CRISPR-based therapeutic target screening is broadly used in cancer drug development. Its application in cancer immunotherapy and precision oncology is blooming. Nevertheless, more effective methods of Cas protein delivery and the development of more accurate and efficient genome-editing tools are needed.
|Authors||Xue VW, Wong SCC, Cho WCS|
|Journal||Expert opinion on therapeutic targets|
|Publication Date||2020 Nov;24(11):1147-1158|