Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy


Immunoglobulin A nephropathy (IgAN) is a common primary glomerular disease contributing to end-stage renal failure. In this study, the induced pluripotent stem cell line GWCMCi001-A from PBMCs of a 4-year-old male patient with IgAN using the episomal plasmids was established, which is an ideal in vitro model to understand the exact pathogenesis of IgAN. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Gao X, Liao X, Zhang J, Lin J, Tan M
Journal Stem cell research
Publication Date 2020 Dec 10;50:102123
PubMed 33359895
DOI 10.1016/j.scr.2020.102123

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