Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions


Two human induced pluripotent stem cell (hiPSC) lines (UCLi016-A and UCLi017-A) were generated from fibroblast cells of 23- and 34-year-old healthy male donors with no known ocular conditions. Fibroblast cells were derived from skin biopsies and reprogrammed using integration free episomal reprogramming. The established iPSC lines were found to express pluripotency markers, exhibit differentiation potential in vitro and display a normal karyotype. These cell lines will act as a control lines for researchers studying ocular diseases. Copyright © 2020 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Méjécase C, Harding P, Sarkar H, Eintracht J, Lima Cunha D, Toualbi L, Moosajee M
Journal Stem cell research
Publication Date 2020 Dec;49:102113
PubMed 33370878
PubMed Central PMC7768179
DOI 10.1016/j.scr.2020.102113

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