Human induced pluripotent stem cells on autologous feeders


These results suggest that autologous fibroblasts can be not only a source for iPS cells but also be feeder layers. Our results provide a possibility to solve the dilemma by using isogenic fibroblasts as feeder layers of iPS cells. This is an important step toward the establishment of clinical grade iPS cells.

Authors Takahashi K, Narita M, Yokura M, Ichisaka T, Yamanaka S
Journal PloS one
Publication Date 2009 Dec 2;4(12):e8067
PubMed 19956543
PubMed Central PMC2780725
DOI 10.1371/journal.pone.0008067

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