Human induced pluripotent stem cells on autologous feeders
Summary
These results suggest that autologous fibroblasts can be not only a source for iPS cells but also be feeder layers. Our results provide a possibility to solve the dilemma by using isogenic fibroblasts as feeder layers of iPS cells. This is an important step toward the establishment of clinical grade iPS cells.
| Authors | Takahashi K, Narita M, Yokura M, Ichisaka T, Yamanaka S |
|---|---|
| Journal | PloS one |
| Publication Date | 2009 Dec 2;4(12):e8067 |
| PubMed | 19956543 |
| PubMed Central | PMC2780725 |
| DOI | 10.1371/journal.pone.0008067 |