Quality Assured Characterization of Stem Cells for Safety in Banking for Clinical Application
Summary
The promise of human pluripotent stem cells to serve as a scalable and renewable starting material for "off the shelf" therapeutic cell products to repair or replace cells and tissues damaged by disease or injury is unparalleled. Whether originating from embryos or the genetic manipulation of adult tissue-derived cells, this prospective impact dictates a comprehensive yet practicable standard of quality assured characterization, blending existing and bespoke standards and considerations. Here, we provide a guide to qualifying the suitability of this resource for human clinical application.
| Authors | Bruce KW, Campbell JD, De Sousa P |
|---|---|
| Journal | Methods in molecular biology (Clifton, N.J.) |
| Publication Date | 2017;1590:79-98 |
| PubMed | 28353263 |
| DOI | 10.1007/978-1-4939-6921-0_6 |