Generation of three iPSC lines from different types of pediatric acute leukemia patients


Leukemia is the most common malignant tumor in childhood. The pathogenesis of leukemia is still unclear. Therefore, it is imperative to establish effective disease models. In our study, we reprogrammed different types of pediatric acute leukemia cells into iPSCs using CytoTune®Sendai virus. All generated iPSCs maintained pluripotency and spontaneous in vivo differentiation capacity. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Li Y, Zhang Y, Li T, Wang X, Bao W, Huang J, Ma Y, Li S, Wang S, Yang Y, Liu Y, Gao Y, Feng H, Li Y
Journal Stem cell research
Publication Date 2021 Aug;55:102460
PubMed 34298433
DOI 10.1016/j.scr.2021.102460

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