Mesenchymal stem cells facilitate the derivation of human embryonic stem cells from cryopreserved poor-quality embryos

Summary

Our data suggest that Y-27632 increases post-thaw embryo survival and that hMSCs may facilitate the efficiency of hESC derivation from frozen poor-quality embryos.

Authors Cortes JL, Sanchez L, Ligero G, Gutierrez-Aranda I, Catalina P, Elosua C, Leone PE, Montes R, Bueno C, Ramos-Mejía V, Maleno I, García-Pérez JL, Menendez P
Journal Human reproduction (Oxford, England)
Publication Date 2009 Aug;24(8):1844-51
PubMed 19401322
DOI 10.1093/humrep/dep107

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