Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome
Summary
Trinucleotide repeat expansion diseases such as fragile X syndrome are of great interest to study since the mechanism of its development is still unknown. IPS cell lines are some of the most convenient models for studying. The ICGi032-A iPS cell line was obtained from the peripheral blood mononuclear cells of the patient affected with fragile X syndrome. ICGi032-A iPS cell line have a normal karyotype, expression of pluripotency markers and can differentiate in vitro into the cells of three germ layers. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Gridina MM, Shitik EM, Lemskaya NA, Minina JM, Grishchenko IV, Dolskiy AA, Shorina AR, Maksimova YV, Yudkin DV |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2021 Dec;57:102615 |
| PubMed | 34864218 |
| DOI | 10.1016/j.scr.2021.102615 |