Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome


Trinucleotide repeat expansion diseases such as fragile X syndrome are of great interest to study since the mechanism of its development is still unknown. IPS cell lines are some of the most convenient models for studying. The ICGi032-A iPS cell line was obtained from the peripheral blood mononuclear cells of the patient affected with fragile X syndrome. ICGi032-A iPS cell line have a normal karyotype, expression of pluripotency markers and can differentiate in vitro into the cells of three germ layers. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Gridina MM, Shitik EM, Lemskaya NA, Minina JM, Grishchenko IV, Dolskiy AA, Shorina AR, Maksimova YV, Yudkin DV
Journal Stem cell research
Publication Date 2021 Nov 29;57:102615
PubMed 34864218
DOI 10.1016/j.scr.2021.102615

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