A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia
Summary
Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL. Copyright © 2022. Published by Elsevier B.V.
| Authors | Kim JH, Kang KW, Lee BH, Park Y, Jung Sung H, Kim BS |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2022 Apr;60:102668 |
| PubMed | 35066240 |
| DOI | 10.1016/j.scr.2022.102668 |