A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia


Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL. Copyright © 2022. Published by Elsevier B.V.

Authors Kim JH, Kang KW, Lee BH, Park Y, Jung Sung H, Kim BS
Journal Stem cell research
Publication Date 2022 Apr;60:102668
PubMed 35066240
DOI 10.1016/j.scr.2022.102668

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