Identification of immune related cells and crucial genes in the peripheral blood of ankylosing spondylitis by integrated bioinformatics analysis

Summary

In this study, we identified DEGs combined with their closely related biological functions and propose that granule-associated proteins and immune infiltration maybe involved in the progression of ankylosing spondylitis. These validated hub genes may provide new perspectives for understanding the molecular mechanisms of ankylosing spondylitis. © 2021 Zheng et al.

Authors Zheng Y, Cai B, Ren C, Xu H, Du W, Wu Y, Lin F, Zhang H, Quan R
Journal PeerJ
Publication Date 2021;9:e12125
PubMed 34589304
PubMed Central PMC8432305
DOI 10.7717/peerj.12125

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