Transcriptional Effects of Candidate COVID-19 Treatments on Cardiac Myocytes
Summary
Transcriptional profiling in hiPSC-CMs treated with COVID-19 drugs identified unfavorable changes with lopinavir/ritonavir and lopinavir/ritonavir/INF-β in key cardiac gene programs that may negatively affect heart function. Copyright © 2022 Jakobi, Groß, Cyganek and Doroudgar.
| Authors | Jakobi T, Groß J, Cyganek L, Doroudgar S |
|---|---|
| Journal | Frontiers in cardiovascular medicine |
| Publication Date | 2022;9:844441 |
| PubMed | 35686037 |
| PubMed Central | PMC9170897 |
| DOI | 10.3389/fcvm.2022.844441 |