UMGi014-C

Registration Summary:

A P E C

The cell line is not submitted yet.

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General

Cell Line
hPSCreg name	UMGi014-C
Cite as:	UMGi014-C (RRID:CVCL_A4ZE)
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	22nd May 2019
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Provider
Generator	University Medical Center Goettingen (UMG)
External Databases
Cellosaurus	CVCL_A4ZE
Wikidata	Q107117263
General Information
Publications	Li Wener et al. Effects of Hydroxychloroquine and Azithromycin on iPSC-derived Cardiomyocytes: Considerations for the Treatment of COVID-19 Patients. . 2021-08-19. Jakobi T et al. Transcriptional Effects of Candidate COVID-19 Treatments on Cardiac Myocytes. Frontiers in cardiovascular medicine. 2022;9:844441. Rapedius M et al. There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments. Frontiers in molecular neuroscience. 2022;15:982316. Li W et al. Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration. Pharmaceuticals (Basel, Switzerland). 2022 Feb 12;15(2). Seibertz F et al. A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes. Communications biology. 2022 Sep 15;5(1):969. Kermani F et al. Membrane remodelling triggers maturation of excitation-contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes. Basic research in cardiology. 2023 Mar 29;118(1):13. Seibertz F et al. Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes. Basic research in cardiology. 2023 Apr 5;118(1):14. Busley AV et al. Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V. Stem cell research. 2023 Jun;69:103108. Busley AV et al. Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V. Stem cell research. 2023 Jun;69:103105. Nakhaei-Rad S et al. Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues. Communications biology. 2023 Jun 21;6(1):657. Chowdhury A et al. Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome. EMBO molecular medicine. 2023 Sep 11;15(9):e17399. Paasche A et al. Acute antiarrhythmic effects of SGLT2 inhibitors-dapagliflozin lowers the excitability of atrial cardiomyocytes. Basic research in cardiology. 2024 Feb;119(1):93-112. Knauer C et al. Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants. Molecular therapy. Nucleic acids. 2024 Mar 12;35(1):102123.
Subclones	UMGi014-C-1 UMGi014-C-2 UMGi014-C-3 UMGi014-C-4 UMGi014-C-5 UMGi014-C-6 UMGi014-C-7 UMGi014-C-8 UMGi014-C-9 UMGi014-C-10 UMGi014-C-11 UMGi014-C-12 UMGi014-C-13 UMGi014-C-14 UMGi014-C-15 UMGi014-C-16 UMGi014-C-17 UMGi014-C-18 UMGi014-C-19 UMGi014-C-20 UMGi014-C-21 UMGi014-C-22 UMGi014-C-23 UMGi014-C-24 UMGi014-C-25 UMGi014-C-26 UMGi014-C-27 UMGi014-C-28 UMGi014-C-29 UMGi014-C-30 UMGi014-C-31 UMGi014-C-32 UMGi014-C-33 UMGi014-C-34 UMGi014-C-35 UMGi014-C-36 UMGi014-C-37 UMGi014-C-38 UMGi014-C-39 UMGi014-C-40 UMGi014-C-41 UMGi014-C-42 UMGi014-C-43 UMGi014-C-44 UMGi014-C-45 UMGi014-C-46 UMGi014-C-47 UMGi014-C-48 UMGi014-C-49 UMGi014-C-50 UMGi014-C-51 UMGi014-C-52 UMGi014-C-53 UMGi014-C-54 UMGi014-C-55 UMGi014-C-56 UMGi014-C-57 UMGi014-C-58 UMGi014-C-59

hIPSC Derivation

General