UMGi014-C

Cell Line

Provider

External Databases

General Information

• Li Wener et al. Effects of Hydroxychloroquine and Azithromycin on iPSC-derived Cardiomyocytes: Considerations for the Treatment of COVID-19 Patients. . 2021-08-19.
• Jakobi T et al. Transcriptional Effects of Candidate COVID-19 Treatments on Cardiac Myocytes. Frontiers in cardiovascular medicine. 2022;9:844441.
• Rapedius M et al. There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments. Frontiers in molecular neuroscience. 2022;15:982316.
• Li W et al. Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration. Pharmaceuticals (Basel, Switzerland). 2022 Feb 12;15(2).
• Seibertz F et al. A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes. Communications biology. 2022 Sep 15;5(1):969.
• Kermani F et al. Membrane remodelling triggers maturation of excitation-contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes. Basic research in cardiology. 2023 Mar 29;118(1):13.
• Seibertz F et al. Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes. Basic research in cardiology. 2023 Apr 5;118(1):14.
• Busley AV et al. Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V. Stem cell research. 2023 Jun;69:103108.
• Busley AV et al. Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V. Stem cell research. 2023 Jun;69:103105.
• Nakhaei-Rad S et al. Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues. Communications biology. 2023 Jun 21;6(1):657.
• Chowdhury A et al. Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome. EMBO molecular medicine. 2023 Sep 11;15(9):e17399.
• Paasche A et al. Acute antiarrhythmic effects of SGLT2 inhibitors-dapagliflozin lowers the excitability of atrial cardiomyocytes. Basic research in cardiology. 2024 Feb;119(1):93-112.
• Schwenzer Niko et al. Nanoscale architecture and dynamics of Ca_V1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy. . 2024-02-28.
• Knauer C et al. Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants. Molecular therapy. Nucleic acids. 2024 Mar 12;35(1):102123.

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