The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research


The Singapore Stem Cell Bank has generated human embryonic stem cell banks from clinical-grade cell lines ESI-017, ESI-035, ESI-049, and ESI-053. All banks were prepared and characterized according to principles of Good Laboratory Practice for quality assurance. Importantly, each cell line has clearly documented and approved ethical provenance and meets recognized standards for performance and safety. The banks are intended to facilitate the translation of stem cell research to clinical medicine by enabling early phase research and development with high-quality, low-cost cells that are also available as clinical-grade stocks.

Authors Sivarajah S, Raj GS, Mathews AJ, Sahib NB, Hwang WS, Crook JM
Journal In vitro cellular & developmental biology. Animal
Publication Date 2010 Apr;46(3-4):210-6
PubMed 20177998
DOI 10.1007/s11626-010-9287-1

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