Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy

Summary

We introduce human muscle models with canonical properties of bona fide skeletal muscle in vivo to study muscle development, maturation, disease and repair. © 2022 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders.

Authors Shahriyari M, Islam MR, Sakib SM, Rinn M, Rika A, Krüger D, Kaurani L, Gisa V, Winterhoff M, Anandakumar H, Shomroni O, Schmidt M, Salinas G, Unger A, Linke WA, Zschüntzsch J, Schmidt J, Bassel-Duby R, Olson EN, Fischer A, Zimmermann WH, Tiburcy M
Journal Journal of cachexia, sarcopenia and muscle
Publication Date 2022 Dec;13(6):3106-3121
PubMed 36254806
PubMed Central PMC9745484
DOI 10.1002/jcsm.13094

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