Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases
Summary
Our findings shed novel insights into the role of progenitors in CCO formation and pave the way for the robust generation of cardiac organoids, as a platform for future applications in disease modelling and drug screening in vitro. © 2022. The Author(s).
| Authors | Ho BX, Pang JKS, Chen Y, Loh YH, An O, Yang HH, Seshachalam VP, Koh JLY, Chan WK, Ng SY, Soh BS |
|---|---|
| Journal | Stem cell research & therapy |
| Publication Date | 2022 Dec 21;13(1):529 |
| PubMed | 36544188 |
| PubMed Central | PMC9773542 |
| DOI | 10.1186/s13287-022-03215-1 |