Generation and characterization of two induced pluripotent stem cell lines from conjunctiva of a retinoblastoma patient
Summary
Retinoblastoma (RB) is a common intraocular malignancy mostly caused by variation of the tumour suppressor gene RB1. In this study, we successfully generated two induced pluripotent stem cell (iPSC) lines from an infant with non-heritable RB. Both cell clones exhibited typical iPSC characteristics with normal karyotypes, consistent pluripotency markers expression and the capability of trilineage differentiation. Copyright © 2023. Published by Elsevier B.V.
| Authors | Xu P, Guo F, Xiao W, Wang Y, Ye K, Mao Y, Zhong X |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2023 Oct;72:103200 |
| PubMed | 37708614 |
| DOI | 10.1016/j.scr.2023.103200 |