Protein-free media for cardiac differentiation of hPSCs in 2000 mL suspension culture

Summary

This study promotes the robustness and upscaling of the cardiomyogenic differentiation process, substantially reduces media costs, and provides an important step toward the clinical translation of hPSC-CMs for heart regeneration. © 2024. The Author(s).

Authors Kriedemann N, Manstein F, Hernandez-Bautista CA, Ullmann K, Triebert W, Franke A, Mertens M, Stein ICAP, Leffler A, Witte M, Askurava T, Fricke V, Gruh I, Piep B, Kowalski K, Kraft T, Zweigerdt R
Journal Stem cell research & therapy
Publication Date 2024 Jul 18;15(1):213
PubMed 39020441
PubMed Central PMC11256493
DOI 10.1186/s13287-024-03826-w

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