Protein-free media for cardiac differentiation of hPSCs in 2000 mL suspension culture
Summary
This study promotes the robustness and upscaling of the cardiomyogenic differentiation process, substantially reduces media costs, and provides an important step toward the clinical translation of hPSC-CMs for heart regeneration. © 2024. The Author(s).
Authors | Kriedemann N, Manstein F, Hernandez-Bautista CA, Ullmann K, Triebert W, Franke A, Mertens M, Stein ICAP, Leffler A, Witte M, Askurava T, Fricke V, Gruh I, Piep B, Kowalski K, Kraft T, Zweigerdt R |
---|---|
Journal | Stem cell research & therapy |
Publication Date | 2024 Jul 18;15(1):213 |
PubMed | 39020441 |
PubMed Central | PMC11256493 |
DOI | 10.1186/s13287-024-03826-w |