Promoting the adoption of best practices and standards to enhance quality and reproducibility of stem cell research
Summary
Advancing the use of human stem cell-based models on preclinical and regulatory testing fields requires the performance of rigorous and reproducible research. Quality standards and reporting best practices should be promoted to ensure the reliability and translatability of stem cell models and results. Strategies to increase awareness and implementation of best practices and standards will require training initiatives and collaboration across relevant stakeholders. Overall, improving the quality and reproducibility of stem cell-based models and methods through best practices and standards will accelerate their adoption in industrial and regulatory contexts and ultimately drive the development of effective therapies and safer chemicals. Copyright © 2025 The Authors. Published by Elsevier Inc. All rights reserved.
| Authors | Selfa Aspiroz L, Mennecozzi M, Batlle L, Corneo B, Healy L, Kotter M, Kurtz A, Ludwig TE, Mummery C, Pera M, Stacey GN, Tristan CA, Whelan M |
|---|---|
| Journal | Stem cell reports |
| Publication Date | 2025 Jul 8;20(7):102531 |
| PubMed | 40513566 |
| PubMed Central | PMC12277813 |
| DOI | 10.1016/j.stemcr.2025.102531 |