Stem cell-derived neural organoids as platforms to investigate glioblastoma invasion and migration: A systematic review
Summary
Human NOs represent promising platforms for modeling glioblastoma invasion in a humanized three-dimensional environment. However, a limited number of studies and methodological heterogeneity hinder reproducibility. Protocol standardization is essential to enhance the translational application of these models. ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
| Authors | Alves ADH, Ennes do Valle NM, Yokota-Moreno BY, Galanciak MCDS, Felix da Silva K, Mamani JB, Sertie AL, de Oliveira FA, Nucci MP, Gamarra LF |
|---|---|
| Journal | World journal of stem cells |
| Publication Date | 2025 Aug 26;17(8):108898 |
| PubMed | 40951702 |
| PubMed Central | PMC12427015 |
| DOI | 10.4252/wjsc.v17.i8.108898 |