Immune activation and response dynamics of human iPSC-derived macrophages in tuberculosis infection models
Summary
These findings support the potential of iMacs as an immunocompetent model for studying mycobacterial infections and as a tool for cell-based TB immunotherapies. © 2026 The Author(s). Clinical & Translational Immunology published by John Wiley & Sons Australia, Ltd on behalf of Australian and New Zealand Society for Immunology, Inc.
| Authors | Paasch D, Schevel H, Riehle A, Costa B, Toufaili H, Gehnen T, Dahlmann J, Pavlou A, Neehus AL, Nguyen AHH, Schiering E, Buchegger T, Bustamante J, Hansen G, Kalinke U, Gulbins E, Grassmé H, Lachmann N |
|---|---|
| Journal | Clinical & translational immunology |
| Publication Date | 2026;15(1):e70071 |
| PubMed | 41541231 |
| PubMed Central | PMC12800570 |
| DOI | 10.1002/cti2.70071 |