Human seminal plasma stimulates the migration of CD11c+ mononuclear phagocytes to the apical side of the colonic epithelium without altering the junctional complexes in an ex vivo human intestinal model
Summary
In conclusion, even if HSP did not perturb the integrity of the human colonic mucosa, it affected the migration of a specific subset of MNPs that express CD11c towards the apical side of the colonic mucosa, which in turn may be involved in pathogen sampling. Copyright © 2023 Baratella, Iannone, Cavarelli, Foglieni, Viganò, Moog, Elmore, Nozza, Alfano, Salonia, Dispinseri and Scarlatti.
| Authors | Baratella M, Iannone V, Cavarelli M, Foglieni C, Viganò P, Moog C, Elmore U, Nozza S, Alfano M, Salonia A, Dispinseri S, Scarlatti G |
|---|---|
| Journal | Frontiers in immunology |
| Publication Date | 2023;14:1133886 |
| PubMed | 37033941 |
| PubMed Central | PMC10073423 |
| DOI | 10.3389/fimmu.2023.1133886 |