Dissemination of the Acinetobacter baumannii isolates belonging to global clone 2 containing AbGRI resistance islands in a referral hospital
Summary
The majority of Acinetobacter baumannii isolates that are resistant to multiple antibiotics belong to one of the two major global clones, namely global clone 1 (GC1) and global clone 2 (GC2). The resistance islands, which contain variable assortments of transposons, integrons, and specific resistance genes, have been characterized in the genome of these GCs. In GC2 A. baumannii, the chromosomally located A. baumannii genomic resistance islands (AbGRIs) carry the genes conferring resistance to older and newer antibiotics. In this context, we tested whether GC2 isolates collected from a referral hospital carry the AbGRIs containing these genes. This study provided evidence for the circulation of the GC2 A. baumannii strains harboring AbGRI resistance islands between different wards of a referral hospital.
| Authors | Naderi G, Asadian M, Seifi A, Ghourchian S, Talebi M, Rahbar M, Abdollahi A, Douraghi M |
|---|---|
| Journal | Microbiology spectrum |
| Publication Date | 2023 Oct 17;11(5):e0537322 |
| PubMed | 37638730 |
| PubMed Central | PMC10581056 |
| DOI | 10.1128/spectrum.05373-22 |