Induced pluripotent stem cell line, ICAGi001-A, derived from human skin fibroblasts of a patient with 2p25.3 deletion and 2p25.3-p23.3 inverted duplication


Skin fibroblasts from a patient with developmental delay and chromosome 2p25.3 deletion syndrome were reprogrammed into induced pluripotent stem cells (iPSCs) and the clonal stem cell line ICAGi001-A (iTAF9-11) was established. ICAGi001-A pluripotency was demonstrated in vitro by three germ layer differentiation capacity. This line is a good model for studying of the developmental delay and brain disorder. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Khabarova AA, Pristyazhnyuk IE, Nikitina TV, Gayner TA, Torkhova NB, Skryabin NA, Kashevarova AA, Babushkina NP, Markova ZG, Minzhenkova ME, Nazarenko LP, Shilova NV, Shorina AR, Lebedev IN, Serov OL
Journal Stem cell research
Publication Date 2019 Jan;34:101377
PubMed 30616144
DOI 10.1016/j.scr.2018.101377

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