Analysis of chromosome microstructures in products of conception associated with recurrent miscarriage
High-resolution genome-wide SNP arrays are effective for detecting novel genetic factors causing recurrent miscarriage. A more appropriate reference CNV list may be necessary to more effectively enrich for CNV likely to cause recurrent miscarriage. The findings confirmed one non-coding RNA cluster as a strong candidate that may contribute to unexplained miscarriages. Gene expression-regulatory mechanisms may play important roles in the pathogenesis of miscarriages. Copyright © 2018 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
|Authors||Sato T, Migita O, Hata H, Okamoto A, Hata K|
|Journal||Reproductive biomedicine online|
|Publication Date||2018 Dec 21;|