|This project intends to transplant human embryonic stem cells derived retinal pigment epitheliums into subretinal space of patients to treat dry age-related macular degeneration(dry-AMD).And we will assess the safety and efficacy of RPE transplants to treat dry AMD.
|This project intends to transplant human embryonic stem cells derived retinal pigment epitheliums into subretinal space to treat age-related macular degeneration(AMD).
Through the statistical analysis EDTRS, BCVA, OCT, ERG, Fluorescein angiography, Ophthalmic AB ultrasound changes between before and after the treatment to assess the efficacy and safety of RPE transplants to treat AMD disease.
|Clinical trials phase
|Start date (estimated)
|age related macular degeneration
|A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.; OMIM mapping confirmed by DO. [SN].
|Other study identifiers
|Chinese Clinical Trial Registry (ChiCTR)
Chinese Academy of Sciences
|Source pluripotent stem cell lines
|Which differentiated cell type is used
|retinal pigment epithelial cell
|An epithelial cell of the retinal pigmented epithelium.
|Estimated number of participants