Clinical study of human (allogeneic) iPS cell-derived cardiomyocyte sheet for ischemic cardiomyopathy

General Information

Clinical trials phase Phase 1
Start date (estimated) 2020-01-10
Clinical feature
Label cardiomyopathy
Link http://purl.obolibrary.org/obo/DOID_0050700
Description A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.; MESH:D009202 added from NeuroDevNet [WAK].

Administrative Information

ICTRP weblink https://trialsearch.who.int/Trial2.aspx?TrialID=JPRN-jRCT2053190081
Other study identifiers
Name jRCT2053190081
Description Japan Registry of Clinical Trials (jRCT)
Source weblink https://jrct.niph.go.jp/en-latest-detail/jRCT2053190081
Regulatory body approval
Name Instisutional review board of Osaka university hospital
Public contact
Email saisentan@tissue.med.osaka-u.ac.jp
Public email saisentan@tissue.med.osaka-u.ac.jp
First name Takuji
Last name Kawamura
Phone +81-6-6879-3154
City Osaka
Country
Japan
Address freetext 2-15, Yamadaoka, Suita, Osaka 565-0871 Osaka Japan

Cells

Which differentiated cell type is used
Label cardiac muscle cell
Link http://purl.obolibrary.org/obo/CL_0000746
Description Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.; This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction.

Recruitment

Recruitment Status Recruiting
Estimated number of participants 10
Contact institutions/departments