ASUi005-A

A P E C

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iPSC Line
hPSCreg name	ASUi005-A
Cite as:	ASUi005-A (RRID:CVCL_UD82)
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	19th May 2018
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Provider
Generator	Arizona State University (ASU)
External iPSC Databases
Cellosaurus	CVCL_UD82
Wikidata	Q93326225
General iPSC Information
Publications	Brookhouser N et al. Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant-Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A). Stem cell research. 2018 Oct;32:145-149. Raman S et al. Using human induced pluripotent stem cells (hiPSCs) to investigate the mechanisms by which Apolipoprotein E (APOE) contributes to Alzheimer's disease (AD) risk. Neurobiology of disease. 2020 May;138:104788. Zhao J et al. APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids. Nature communications. 2020 Nov 2;11(1):5540. İş Özkan et al. Gliovascular transcriptional perturbations in Alzheimer’s disease reveal molecular mechanisms of blood brain barrier dysfunction. Nature Communications. 2024-06-20.