BTHBIOi006-A

RDH12-LY-M-BIPS-C2-211109

The cell line is not validated yet.

General

Cell Line

hPSCreg name BTHBIOi006-A
Cite as:
BTHBIOi006-A
Alternative name(s)
RDH12-LY-M-BIPS-C2-211109
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.
Last update 30th September 2025
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Provider

Generator Beijing Institute of Ophthalmology for BeijingTongren Hospital (BTHBIO)
Owner Beijing Institute of Ophthalmology for BeijingTongren Hospital (BTHBIO)
Distributors
Derivation country China

External Databases

BioSamples SAMEA120272607

General Information

* Is the cell line readily obtainable for third parties?
No

Donor Information

General Donor Information

Sex female
Ethnicity Asian

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
The donor is a carrier of a disease-associated mutation.
Stage
unknown
Genetic variants
RDH12 c.437T>A,p.V146D/c.524C>T,p.S175L

Karyotyping (Donor)

Has the donor karyotype been analysed?
Yes
46,XX

External Databases (Donor)

BioSamples SAMEA120272608

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? Yes
Do you (Depositor/Provider) hold the original Donor Consent Form? Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
* Does consent expressly prevent the derivation of pluripotent stem cells? No
* Does consent pertain to a specific research project? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? 首都医科大学附属北京同仁医院伦理委员会
Approval number T R E C K Y 2 0 2 1 - 0 8 8
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type (free text) Blood

Reprogramming method

Vector type Non-integrating
Vector Episomal
Genes
Is reprogramming vector detectable?
Yes
Methods used
Sequencing

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium Essential 8™

Characterisation

No characterisation data could be found.

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46,XX

Other Genotyping (Cell Line)