HVRDe009-A-3

GBA-KO/C50

The cell line is not validated yet.

General

iPSC Line

hPSCreg name HVRDe009-A-3
Cite as:
HVRDe009-A-3
Alternative name(s)
GBA-KO/C50
iPSC line type Human embryonic stem cell (hESC)
Similar iPSC lines No similar lines found.
Last update 10th March 2026
User feedback
No feedback available yet.

Login to share your feedback, experiences or results with the research community.

Provider

Generator University Medical Center Groningen (UMCG)
Owner University Medical Center Groningen (UMCG)
Distributors

External iPSC Databases

BioSamples SAMEA121957983

General iPSC Information

* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed
Subclone of

iPSC Genetic Modification

Genetic modifications not related to a disease
Gene knock-out
1q21
CRISPR-associated (CRISPR/Cas) System

Donor Information

General Donor Information

Sex female

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
Yes

External Databases (Donor)

BioSamples SAMEA8944198

Ethics

Also have a look at the ethics information for the parental line HVRDe009-A .
Is there an MTA available for the cell line? No
Are you aware of any constraints on the use or distribution of the cell line from the owner or any parties identified in the query above? No

hESC Derivation

The source cell information can be found in the parental cell line HVRDe009-A.

iPSC Culture Conditions

Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzymatically
ReLeSR
Medium mTeSR™ 1
Has Rock inhibitor (Y27632) been used at passage previously with this iPSC line?
Yes
Has Rock inhibitor (Y27632) been used at cryo previously with this iPSC line?
No
Has Rock inhibitor (Y27632) been used at thaw previously with this iPSC line?
Yes

iPSC Characterisation

Analysis of undifferentiated iPSCs
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
Differentiation Potency
Hindgut
Ont Id: NCIT_C34188
In vitro directed differentiation
Fibroblast
Ont Id: NCIT_C12482
In vitro spontaneous differentiation
Neural Crest Cell
Ont Id: NCIT_C33937
In vitro directed differentiation

Certificate of Analysis

Is there a certificate of analysis available?
Yes
Passage:

Genotyping

Karyotyping (iPSC Line)

Has the iPSC line karyotype been analysed?
Yes
46, XX

Other Genotyping (iPSC Line)