KSCBi014-A

Registration Summary:

A P E C

LQT01-hiPSC

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	KSCBi014-A
Cite as:	KSCBi014-A (RRID:CVCL_B5RZ)
Alternative name(s)	LQT01-hiPSC
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	15th October 2021
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Provider
Generator	National Stem Cell Bank (KSCB)
External iPSC Databases
Cellosaurus	CVCL_B5RZ
Wikidata	Q111733560
General iPSC Information
Publications	Lee Y et al. Establishment of a human-induced pluripotent stem cell line, KSCBi014-A, from a long QT syndrome type 2 patient harboring a KCNH2 mutation. Stem cell research. 2021 Dec;57:102570. (reference publication) Song Y et al. Deciphering Common Long QT Syndrome Using CRISPR/Cas9 in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Frontiers in cardiovascular medicine. 2022;9:889519. Park Na Kyeong et al. Translation reinitiation in c.453delC frameshift mutation of KCNH2 producing functional hERG K+ channels with mild dominant negative effect in the heterozygote patient-derived iPSC cardiomyocytes. Human Molecular Genetics. 2024-01-07. Park Na Kyeong et al. Human induced pluripotent stem cell-cardiomyocytes for cardiotoxicity assessment: a comparative study of arrhythmiainducing drugs with multi-electrode array analysis. The Korean Journal of Physiology & Pharmacology. 2025-03-01. Park Yun-Gwi et al. A machine learning platform for genotype-specific cardiotoxicity risk prediction using patient-derived iPSC-CMs. Journal of Advanced Research. 2026-04-00.
* Is the cell line readily obtainable for third parties?	No

iPSC Derivation

General