LUMCi064-A-2

ISO3LUMC0216iAPOL05

The cell line is not validated yet.

General

iPSC Line

hPSCreg name LUMCi064-A-2
Cite as:
LUMCi064-A-2
Alternative name(s)
ISO3LUMC0216iAPOL05
iPSC line type Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines
LUMCi064-A-1
(ISO1LUMC0216iAPOL05)
Donor's gene variants:
APOL1
Donor diseases:
chronic kidney disease
LUMCi064-A
(LUMC0216iAPOL)
Donor's gene variants:
APOL1
Donor diseases:
chronic kidney disease
LUMCi063-A
(LUMC0214iAPOL)
Donor's gene variants:
APOL1
Donor diseases:
chronic kidney disease
Last update 25th July 2025
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Provider

Generator Leiden University Medical Center (LUMC)

External iPSC Databases

BioSamples SAMEA118800063

General iPSC Information

* Is the cell line readily obtainable for third parties?
No
Subclone of

iPSC Genetic Modification

Disease/phenotype related modifications
Genetic modifications
APOL1 (target)
Isogenic modification
APOL1 G2G2 variant is corrected to G0G0

Donor Information

General Donor Information

Sex female

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
APOL1-mediated kidney disease
The donor is a carrier of a disease-associated mutation and affected.
Synonyms
  • CKD
  • CRF
  • chronic kidney failure
  • chronic renal disease
  • chronic renal failure syndrome
  • renal failure - chronic
show more synonyms
Genetic variants
APOL1 (target)
Homozygous
G2 Variant

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA118800061

Ethics

Also have a look at the ethics information for the parental line LUMCi064-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

iPSC Derivation

General

The source cell information can be found in the parental cell line LUMCi064-A.

Reprogramming method

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

iPSC Culture Conditions

iPSC Characterisation

No characterisation data could be found for this subclone. Please open parental cell line LUMCi064-A .

Genotyping

Karyotyping (iPSC Line)

Has the iPSC line karyotype been analysed?
Yes

Other Genotyping (iPSC Line)